Certainly, they are those who will be the greatest losers in the Hereafter.

In this verse Allah informs about the direction of their end. He explains that they are the greatest losers among mankind in their transaction for the abode of the Hereafter. 

That is because they exchanged the highest levels (of Paradise) for the lowest levels (of Hell) and they substituted the pleasure of Gardens (of Paradise) for the fierce boiling water (of Hell). 

They exchanged the drink of sealed nectar with the fierce hot wind, boiling water, and a shade of black smoke. 

They chose food from the filth of dirty wounds instead of wide-eyed lovely maidens. They preferred <b>Hawiyah</b> (a pit in Hell) instead of lofty castles. 

They chose the anger of Allah and His punishment over nearness to Him and the blessing of gazing at Him. 

Therefore, it is no injustice that such people should be the greatest losers in the Hereafter